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Discovery of anti-inflammatory compounds from the stem bark of Garcinia latissima

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Garcinia latissima Miq. has been traditionally used by local communities in Indonesia for wound healing and to relieve itching. A phytochemical investigation of the stem bark of G. latissima led to the isolation of tocotrienol and triterpenoid derivatives, including previously undescribed metabolites. Among the isolates, (20R)-eupha-8,25-diene-3β,24ξ-diol suppressed nitric oxide production in LPS-stimulated RAW 264.7 cells …

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Artificial three-dimensional skin from fish gelatin-hyaluronic acid porous scaffold

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Artificial three-dimensional (3D) skin has been used as an alternative material for toxicity testing, studying skin diseases, and skin tissue engineering. The 3D skin can be fabricated using supporting materials that facilitate cell attachment, promote nutrients and air permeation, and eventually accommodate 3D cellular construction. Herein, fish gelatin-hyaluronic acid porous scaffold were employed as the …

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Discovery of New Alpha-Glucosidase Inhibitors from Cannabis Leaves Leading to Structural and Mechanistic Insights

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Thailand has permitted the use of Cannabis sativa for medical purposes, creating opportunities for broader research on its potential applications. In this study, 11 new compounds of the cannabinoid and spiroindane classes were identified. These include substances with inhibitory activity against α-Glucosidase, an enzyme associated with diabetes. Molecular docking studies, supported by the research group …

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One class self-organizing maps with Monte Carlo permutation for gemstone classification using Raman spectroscopy

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Accurately identifying gemstones is important for authentication and quality control. In this study, we developed an artificial intelligence method that uses self-organizing maps (SOMs) combined with Monte Carlo testing to classify gemstones from their Raman vibrational patterns. The model was optimized for map size and training cycles, and its reliability was evaluated through repeated random …

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Game-Changing Hepatitis B Virus Electrochemical Sensor Developed from Laser-Induced Graphene

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 Dr. Pumidech Puthongkham’s research group has been pioneered the application of Laser-Induced Graphene (LIG) in electrochemical biosensors in our department! We’ve just unveiled a high-performance immunosensor for Hepatitis B surface antigen (HBsAg) detection. Why it’s a Breakthrough:  Ultra-Sensitive & Fast: Functionalizing more carboxyl group on LIG electrode enhanced HBV antibody immobilization, yielding an incredibly low …

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Modified MOF catalysts: CO2 to value-added products

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This research focuses on the design and modification of high surface area, porous materials known as metal-organic frameworks (MOFs). The objective is to utilize these materials as catalysts to convert carbon dioxide (CO2) into high-value cyclic carbonates, which are crucial for the polymer and battery industries. MOFs typically suffer from diffusion limitations because their pores …

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Assoc. Prof. Dr. Stefano Cinti

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Associate Professor Dr. Stefano Cinti stefano.cinti@unina.it Department of Pharmacy, University of Naples Federico II, Italy electrochemical sensors, paper-based devices, nanomotors, and nanomaterials Welcome to the Lab

Professor Dr. Syuji Fujii

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Professor Dr. Syuji Fujii syuji.fujii@oit.ac.jp Department of Applied Chemistry, Faculty of Engineering, Osaka Institute of Technology, Japan colloid and interfacial chemistry, polymer chemistry https://research-db.oit.ac.jp/html/100000883_en.html